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Wednesday 4 July 2012

Doctors pull plug on the donor liver

CHENNAI: Doctors at the city transplanted from a donor liver to a child two years old, Oman, two months ago. It was announced on Tuesday it will soon stop some of the anti-rejection drugs Yasmen Said Al Said Nakad Amari has been on what your body rejecting the new liver.

This would be disastrous in a standard liver transplant, but doctors expect Yasmen own liver to regenerate and make redundant the transplant. The transplanted liver is deliberately allowed to wither.

Yasmen looked cheerful in a press conference called by the doctors on Tuesday to announce the success of auxiliary liver transplantation. Yasmen is among a small number of children who have been subjected to the usual procedure in which the donor liver does its job for a while and then allowed to disappear.


"It is a complex surgery and surgeons have to be carefully selected patients. Is why this type of surgery is rare," said transplant surgeon Dr. Mohamed Rela Global Hospitals, who has done similar procedures in the UK .

Yasmen, now spoiled by paramedics, was an ideal patient for surgery. She developed acute liver failure due to hepatitis viral disease that causes inflammation of the liver. Although most patients with hepatitis A recover within three months, one in 1000 developed acute liver failure. Yasmen hepatic led to brain swelling, jaundice, respiratory problems and reduced urine output. She turned on the fan for over 15 days and received dialysis before she was airlifted from Oman to global hospital Chennai.

The pediatric intensive care team in hospitals Global Yasmen stabilized for transplantation. During the 10-hour surgery, Dr. Rela and his team removed a portion of the liver Yasmen and replaced by a small portion of his uncle Mohammed Saeed Salon Nakad liver. Yasmen prescribed regular doses of immunosuppressive drugs until their own liver regenerates and is not dependent on the transplanted organ.



"You can take a year or more," said Dr. Rela. "When you grow large enough to support the body, we will remove your immune suppression. The child will be given the opportunity to get your liver in a healthy state."

Doctors say the postoperative period was "stormy". The doctors could not Yasmen of mechanical ventilation for more than a month. "Your blood pressure and heart did not stabilize in the early days. We had to be careful to avoid infection," said Dr. Naresh Shanmugam team care hospital pediatric intensive liver.

But Yasmen liver function returned to normal slowly. At present, the liver from a donor who is doing most of the work, but the girl's liver has recovered 6% of its function. "Most patients who undergo transplantation recover this normally, but in some cases patients require surgery to remove the donor liver. Yasmen We'll have to watch," said Dr. Shanmugam.

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